Peptide Nucleic Acids as miRNA Target Protectors for the Treatment of Cystic Fibrosis
نویسندگان
چکیده
منابع مشابه
Peptide Nucleic Acids as miRNA Target Protectors for the Treatment of Cystic Fibrosis.
Cystic Fibrosis (CF) is one of the most common life shortening conditions in Caucasians. CF is caused by mutations in the CF Transmembrane Conductance Regulator (CFTR) gene which result in reduced or altered CFTR functionality. Several microRNAs (miRNAs) downregulate the expression of CFTR, thus causing or exacerbating the symptoms of CF. In this context, the design of anti-miRNA agents represe...
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ژورنال
عنوان ژورنال: Molecules
سال: 2017
ISSN: 1420-3049
DOI: 10.3390/molecules22071144